Mother-infant hepatitis C transmission: Second generation research

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Mother-to-infant transmission of hepatitis C virus.

The rate of mother-to-infant transmission of hepatitis C virus (HCV) is approximately 5%, but is higher when the mother is co-infected with HIV Vertical transmission is restricted to infants whose mothers are viraemic. The risk of transmission increases with increasing maternal viral load but a specific cut-off value predicting infection cannot be defined. There is no specific HCV genotype whic...

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Mother to newborn and infant transmission of hepatitis B infections.

A review of maternal transmission of HBV infections revealed that transmission rates are high in many countries in Asia, due mainly to the high prevalence of carriers and high HBeAg rates in these carriers. Transmission can occur in the anteparturn, intrapartum and postpartum periods. About 90% occurs at the time of birth, and 5-10% are the result of in-utero infection. 90% of newborns infected...

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Maternal-infant transmission of hepatitis C virus infection.

Mother-to-infant transmission of hepatitis C virus (HCV) is comparatively uncommon. The prevalence of antibody to HCV (anti-HCV) in pregnant women is 0.1% to 2.4%, although in some endemic areas it is much higher. The proportion of women with anti-HCV who have active infection with viremia is 60% to 70%. Transmission of HCV occurs only when serum HCV RNA is detectable and may be related to high...

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Increased risk of mother-to-infant transmission of hepatitis C virus by intrapartum infantile exposure to maternal blood.

Virological and clinical data from 73 hepatitis C virus (HCV)-infected pregnant women who gave birth to 75 children were merged retrospectively, by logistic regression analysis, to investigate risk factors for vertical transmission of HCV. Eighty-two percent of the HCV-infected mothers were HCV-RNA-positive during pregnancy, and 10% were coinfected with human immunodeficiency virus (HIV). Nine ...

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Increased Risk for Mother-to-Infant Transmission of Hepatitis C Virus Among Medicaid Recipients ― Wisconsin, 2011–2015

State surveillance during the last 10 years reveals a nationwide increase in hepatitis C virus (HCV) infection among young adults (1). The proportion of infants born to HCV-infected women is also increasing nationally (2). To estimate the proportion of infants born to HCV-infected women and the frequency of confirmed HCV infection in their infants, maternal name and date of birth from HCV repor...

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ژورنال

عنوان ژورنال: Hepatology

سال: 1999

ISSN: 0270-9139,1527-3350

DOI: 10.1002/hep.510290357